Tationil 600mg/4ml 10 ampoules

Tationil Composition
One bottle with powder contains the active substance – glutathione reduced sodium salt 0.646 g,

Dosage form
Lyophilized powder for solution for intravenous administration 600 mg complete with solvent – water for injection 4 ml

Pharmacotherapeutic group
Antidotes
Code: ATX V03AB32

Indications for use
It is used as the main agent in the “Milan cocktail”, complementing the action of ezaphosphine. It is used intravenously according to a special scheme.

Glutathione is indicated as a means for intoxication of the following substances: ethyl alcohol, organophosphorus agents, acetaminophen, special chemotherapeutic agents, cytotoxic and anti-tuberculosis drugs, psychotropic, neuroleptic drugs, antidepressants.

Glutathione is also effective in the prevention or treatment of lesions caused by radioactive irradiation.

It is used in hepatopathy.

Method of administration and dosage
The daily dose of Tationil (tationil) usually recommended for patients receiving chemotherapy with cisplatin and related compounds is 1.5 g / m² (equivalent to 2.5 g) by slow intravenous infusion.

The dose, however, depends on the age, weight and clinical condition of the patient, as well as the dose and schedule of administration of chemotherapeutic agents.

In case of simultaneous use of glutathione and chemotherapeutic agent, intravenous infusion of Tationil should be performed 15-30 minutes before the start of chemotherapy.

In case of long-term treatment, it is possible to reduce the dose of the drug (600 mg or 300 mg), which can be administered intramuscularly or slowly intravenously.