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Mexidol Composition:
1 ml of solution contains ethylmethylhydroxypyridine succinate in terms of 100% of the substance – 50 mg; Excipients: succinic acid, edetate disodium, water for injections.
Indications
In the combined therapy:
– acute myocardial infarction (1 day);
– ischemic stroke;
– vascular encephalopathy (including atherosclerotic);
– light and mild cognitive disorders of various origins.
Dosage & Administration
14 days against a background of traditional therapy of myocardial infarction.
During the first 5 days to achieve maximum effect, it is desirable to introduce the drug, in the next 9 days .
B / in a drug infusion is carried out by dropping slowly (to avoid side-effects), with 0.9% sodium chloride rum or 5% dextrose-set p (glucose) in a volume of 100-150 ml for 30-90 min . If necessary, may slow bolus formulation of at least 5 minutes.
Introduction formulation (w / or w / o) is carried out 3 times a day at every 8 hours daily therapeutic dose is 9.6 mg / kg body weight, single -. 2.3 mg / kg. The maximum daily dose should not exceed 800 mg, single – 250 mg.
In acute stroke (ischemic stroke) Mexicor used in the complex therapy in the first 2-4 days / drip 200-300 mg 2-3 times a day, and then – in / m to 100 mg 3 times a day. The period of treatment – 10-14 days. Subsequently, the drug is prescribed for 14 days and 100 mg 3 times a day in 100 mg capsules two times daily – for 7 days. The frequency and duration of refresher courses determined by the physician depending on the disease.
Contradictions
Increased individual sensitivity to the drug, hepatic or renal insufficiency, children under 18 years of age (efficacy and safety have not been established) during pregnancy and lactation.
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