Lasix (furosemide) Composition:
active substance: furosemide;
1 tablet contains furosemide in terms of 100% dry matter – 40 mg
auxiliary substances: corn starch, microcrystalline cellulose, magnesium stearate, povidone, polyethylene glycol (macrogols), lactose.
Indications:
Edema in chronic congestive heart failure (if treatment with diuretics is necessary).
Edema in chronic renal failure.
Acute renal failure, including in pregnant women or during childbirth.
Swelling with nephrotic syndrome (if treatment with diuretics is necessary).
Edema in liver diseases (if necessary, to supplement treatment with aldosterone antagonists).
Arterial hypertension.
Contraindications
Hypersensitivity to furosemide or other components that make up the drug.
Hypersensitivity to sulfonamides (eg, sulfonamide antibiotics or sulfonylureas) due to possible cross-sensitivity to furosemide.
Hypovolemia or dehydration.
Anuria or renal failure with anuria, in which there is no therapeutic response to furosemide.
Renal failure due to poisoning with nephrotoxic or hepatotoxic drugs or renal failure associated with hepatic coma.
Severe hypokalemia.
Severe hyponatremia.
Precomatose and coma associated with hepatic encephalopathy.
Method of administration and dosage:
The dosage regimen is set by the doctor individually, depending on the severity of the water-electrolyte balance disorders, the amount of glomerular filtration, the severity of the patient’s condition. The drug is usually used on an empty stomach. For adults, the maximum total daily dose should not exceed 1500 mg.
Special dosage recommendations for adults.
For edema in chronic congestive heart failure, the recommended initial dose of the drug for oral administration is 40 mg per day. If necessary, you can adjust the dose depending on the therapeutic response of the patient. It is recommended to take the daily dose, divided into 2 or 3 doses.
With edema in chronic renal failure
The dose must be carefully titrated to ensure a gradual initial fluid loss. For adult patients, this means the administration of a dose that leads to a daily decrease in body weight of about 2 kg (about 280 mmol Na +). The recommended starting daily oral dose is 40-80 mg. If necessary, you can adjust the dose depending on the patient’s therapeutic response. The total daily dose can be administered at a time or divided into 2 doses. For patients on hemodialysis, the total daily oral dose is 250-1500 mg.
In acute renal failure, before starting the use of the drug, it is necessary to compensate for hypovolemia, hypotension and significant electrolyte and acid-base imbalance. It is recommended to make the transition from intravenous to oral administration as soon as possible.
For edema with nephrotic syndrome, the recommended starting dose for oral administration is 40-80 mg per day. If necessary, you can adjust the dose depending on the therapeutic response of the patient. The total daily dose can be administered at a time or divided into several doses.
For edema in liver diseases, is prescribed as an adjunct to therapy with aldosterone antagonists in cases where the use of aldosterone antagonists alone is not enough. To prevent complications such as orthostatic hypotension or electrolyte and acid-base imbalance, the dose should be titrated carefully to ensure gradual initial fluid loss. For adult patients, this means the appointment of such a dose, which leads to a daily decrease in body weight by about 0.5 kg. The recommended starting daily oral dose is 40 to 80 mg. If necessary, you can adjust the dose depending on the therapeutic response of the patient. The daily dose can be administered as a single dose or divided into several doses. The drug in this dosage form should be prescribed to children weighing more than 10 kg. For children, the recommended oral dose of furosemide is 2 mg / kg body weight, but the maximum daily dose should not exceed 40 mg.
Shelf life:
4 years.
Do not use after the expiration date printed on the packaging
Storage conditions:
In original packaging at a temperature not exceeding 25 ° C.
