Isotretinoin Acnetin 8mg 30 capsules

Composition
active ingredient: isotretinoin;

1 capsule contains 8 mg of isotretinoin;

excipients: stearyl macrogolglycerides, refined soybean oil, sorbitan oleate, gelatin, titanium dioxide (E 171), red iron oxide (E 172) (for 8 mg dosage), indigo carmine (E 132) (for 16 mg dosage), yellow iron oxide (E 172) (for 16 mg dosage).

Indications
Severe forms of acne (including nodular and conglobatic acne, acne with a tendency to permanent scarring) that are not amenable to standard treatment methods (systemic antibacterial therapy, topical treatment).

Method of administration and dosage
Standard dosage regimen

Isotretinoin treatment should be prescribed and carried out only by a doctor who has experience in the use of systemic retinoids for the treatment of severe acne and is fully aware of the risks of retinoid therapy and the requirements for monitoring the patient’s condition.

Aknetin® is prescribed to adults and children over 12 years of age, starting with a dose of 0.4 mg/kg per day. Capsules should be taken with meals 1 or 2 times a day.

In case of missing a prescribed dose of the drug, it is not recommended to take a double dose of the drug!

The therapeutic response to Aknetin®, as well as undesirable effects, are dose-dependent and have varying degrees of severity. This requires individual dose adjustment during treatment. For most patients, the dose is from 0.4 to 0.8 mg/kg per day.

Often, at the beginning of treatment, a short-term exacerbation of the disease is noted. The effectiveness of treatment and side effects vary from patient to patient, so after 4 weeks of therapy, the dose should be individually adjusted to adults from 0.1 to 1 mg/kg per day. The maximum daily dose of 1 mg/kg can only be prescribed for a limited time.

Usually, the course of treatment lasts from 16 to 24 weeks. When evaluating the results of therapy, it should be remembered that the effect of the drug often persists after discontinuation of treatment. In this regard, a repeated course should be prescribed no earlier than after 8 weeks.

For most patients, only one course of treatment is sufficient to get rid of acne. In case of confirmed relapse, a repeated course of isotretinoin can be offered. The dose for repeated treatment should be prescribed in accordance with the above recommendations.

For patients who do not tolerate the recommended doses well, treatment can be continued at a lower dose, which should be accompanied by an increase in the duration of treatment and may, accordingly, lead to an increase in the risk of relapse. For such patients, the course of treatment should be continued with the appointment of the maximum acceptable dose.